Angiomatoid fibrous histiocytoma – an adolescent with an unusual presentation and course

Sara Isabel de Almeida, Paediatric Department, Hospital Beatriz Ângelo, Loures, Portugal
Sofia Cochito Sousa, Paediatric Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon, Portugal
Cristina Mendes, Department of Paediatric Oncology, Portuguese Institute of Oncology, Lisbon, Portugal
Rafael Cabrera, Department of Paediatric Oncology, Portuguese Institute of Oncology, Lisbon, Portugal
Ana Lacerda, Department of Paediatric Oncology, Portuguese Institute of Oncology, Lisbon, Portugal

Introduction: Angiomatoid fibrous histiocytoma is a rare soft tissue neoplasm, which usually presents as an indolent mass in children and young adults and is often mistaken for a hematoma or hemangioma. Suspecting this diagnosis from imaging findings may be challenging, leading to diagnostic delays. Prognosis is generally favorable and metastases are infrequent at presentation. Case report: We describe the case of an adolescent who presented with a two-month history of a growing mass in the left scapular region, where diagnosis was made possible through surgical biopsy. Discussion: There were loco-regional lymphatic invasions and lung metastases at admission, and despite surgery and chemotherapy the disease rapidly progressed to death.

Keywords: Child. Histiocytoma malignant fibrous. Neoplasm metastasis. Soft tissue injuries. Soft tissue neoplasms.