Anorexia nervosa is an eating disorder associated with several medical conditions that are directly related to weight loss and starvation, including cardiovascular events and peripheral vascular disorders. We present a case report of a 15-year-old girl with anorexia nervosa and a severe peripheral vasospasm event which correlates directly with a decrease in body mass index without any other risk factor identified. Severe ischemia, as a complication of anorexia nervosa, is not common but has been reported in previous case reports, however, with other risk factors besides anorexia nervosa. Even though the exact pathophysiological mechanisms that predispose patients to vasculopathy in anorexia nervosa are still unknown, the likelihood of these complications increases as the patient further loses weight. Therefore, nutritional rehabilitation is fundamental to avoid these complications.